Presynaptic NMDA receptors and spike timing-dependent long-term depression at cortical synapses

Presynaptic NMDA receptors and spike timing-dependent long-term depression at cortical synapses

It has recently been discovered that some forms of timing-dependent long-term depression (t-LTD) require presynaptic N-methyl-D-aspartate (NMDA) receptors. In this review, we discuss the evidence for the presence of presynaptic NMDA receptors at cortical synapses and their possible role in the induc...

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Bibliographic Details
Main Authors: Antonio Rodriguez Moreno, Abhishek Banerjee, Ole Paulsen
Format: Article
Language:English
Published: Frontiers Media S.A. 2010-06-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
STDP
synaptic plasticity
NMDA receptor
presynaptic mechanisms
t-LTD
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnsyn.2010.00018/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnsyn.2010.00018/full

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