Adipose-Derived Stem Cells Based on Electrospun Biomimetic Scaffold Mediated Endothelial Differentiation Facilitating Regeneration and Repair of Abdominal Wall Defects via HIF-1α/VEGF Pathway

Adipose-Derived Stem Cells Based on Electrospun Biomimetic Scaffold Mediated Endothelial Differentiation Facilitating Regeneration and Repair of Abdominal Wall Defects via HIF-1α/VEGF Pathway

Application of synthetic or biological meshes is the main therapy for the repair and reconstruction of abdominal wall defects, a common disease in surgery. Currently, no ideal materials are available, and there is an urgent need to find appropriate ones to satisfy clinical needs. Electrospun scaffol...

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Bibliographic Details
Main Authors: Wenpei Dong, Zhicheng Song, Suihong Liu, Ping Yu, Zhipeng Shen, Jianjun Yang, Dongchao Yang, Qinxi Hu, Haiguang Zhang, Yan Gu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
abdominal wall defects
biomimetic scaffold
tissue engineering
adipose-derived stem cells
endothelial differentiation
angiogenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2021.676409/full

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