Novel Insights into Beta 2 Adrenergic Receptor Function in the rd10 Model of Retinitis Pigmentosa

Novel Insights into Beta 2 Adrenergic Receptor Function in the rd10 Model of Retinitis Pigmentosa

<b>Background</b>: In retinitis pigmentosa (RP), inherited rod death is followed by cone loss and blindness. Why cones die is still a matter of consideration. Here, we investigate the pathogenic role of the sympathetic transmission in the rd10 mouse model of RP. <b>Methods</b>...

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Bibliographic Details
Main Authors: Maurizio Cammalleri, Massimo Dal Monte, Rosario Amato, Dominga Lapi, Paola Bagnoli
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cells
Subjects:
retina degenerative disease
sympathetic transmission
desensitization
HIF-1α stabilization
inflammatory process
cone loss
Online Access:https://www.mdpi.com/2073-4409/9/9/2060

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