Hypoxia-Ischemia Induced Age-Dependent Gene Transcription Effects at Two Development Stages in the Neonate Mouse Brain

Hypoxia-Ischemia Induced Age-Dependent Gene Transcription Effects at Two Development Stages in the Neonate Mouse Brain

Human brain lesions in the perinatal period result in life-long neuro-disabilities impairing sensory-motor, cognitive, and behavior functions for years. Topographical aspects of brain lesions depend on gestational age at the time of insult in preterm or term infants and impaired subsequent steps of...

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Bibliographic Details
Main Authors: Nicolas Dupré, Céline Derambure, Bérénice Le Dieu-Lugon, Michelle Hauchecorne, Yannick Detroussel, Bruno J. Gonzalez, Stéphane Marret, Philippe Leroux
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Molecular Neuroscience
Subjects:
brain-development
cholesterol-biosynthesis
encephalopathy
hypoxia-ischemia
inflammation
mouse
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2020.587815/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2020.587815/full

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