Matrix Metalloproteinases are required for membrane motility and lumenogenesis during Drosophila heart development.

Matrix Metalloproteinases (Mmps) degrade glycoproteins and proteoglycans of the extracellular matrix (ECM) or cell surface and are crucial for morphogenesis. Mmps and their inhibitors are expressed during early stages of cardiac development in vertebrates and expression is altered in multiple congen...

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Bibliographic Details
Main Authors: Qanber S Raza, Jessica L Vanderploeg, J Roger Jacobs
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5305246?pdf=render