Efficacy of Divinylbenzenic Resin in Removing Indoxyl Sulfate and P-cresol Sulfate in Hemodialysis Patients: Results from an In Vitro Study and an In Vivo Pilot Trial (xuanro4-Nature 3.2)

Efficacy of Divinylbenzenic Resin in Removing Indoxyl Sulfate and P-cresol Sulfate in Hemodialysis Patients: Results from an In Vitro Study and an In Vivo Pilot Trial (xuanro4-Nature 3.2)

High serum levels of microbiota-derived uremic toxins, indoxyl sulfate (IS) and p-cresyl sulfate (PCS), are associated with chronic kidney disease (CKD) progression and cardiovascular complications. IS and PCS cannot be efficiently removed by conventional hemodialysis (HD), due to their high binding...

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Bibliographic Details
Main Authors: Maria Teresa Rocchetti, Carmela Cosola, Ighli di Bari, Stefania Magnani, Vanessa Galleggiante, Letizia Scandiffio, Giuseppe Dalfino, Giuseppe Stefano Netti, Mauro Atti, Roberto Corciulo, Loreto Gesualdo
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Toxins
Subjects:
indoxyl sulfate
p-cresyl sulfate
microbiota
synbiotic
sorbents
hemodialysis
chronic kidney disease
Online Access:https://www.mdpi.com/2072-6651/12/3/170

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