THE INFLUENCE OF CROSS-PLATFORM MICROARRAY DATA INTEGRATION ON GENE EXPRESSION VALUES IN HUMAN BREAST CANCER SAMPLES

THE INFLUENCE OF CROSS-PLATFORM MICROARRAY DATA INTEGRATION ON GENE EXPRESSION VALUES IN HUMAN BREAST CANCER SAMPLES

Introduction. Currently advances in different fields of biology and medicine accumulated large amount of high-throughput microarray datasets. It allows comparing, merging and analyzing such data in order to get more informative and statistically significant results. However, the process of cross-pla...

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Main Authors: A. O. Frolova, V. S. Bondarenko, M. Yu. Obolenska
Format: Article
Language:English
Published: Ukrmedknyha Publishing House 2016-08-01
Series:Medična Informatika ta Inženerìâ
Online Access:http://ojs.tdmu.edu.ua/index.php/here/article/view/6476
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spelling doaj-df13af6e3ad54e87bf5dec6829c324122020-11-24T23:53:20ZengUkrmedknyha Publishing HouseMedična Informatika ta Inženerìâ1996-19601997-74682016-08-010210.11603/mie.1996-1960.2016.2.64765842THE INFLUENCE OF CROSS-PLATFORM MICROARRAY DATA INTEGRATION ON GENE EXPRESSION VALUES IN HUMAN BREAST CANCER SAMPLESA. O. Frolova0V. S. Bondarenko1M. Yu. Obolenska2Інститут молекулярної біології і генетики НАН УкраїниКиївський національний університет імені Тараса ШевченкаІнститут молекулярної біології і генетики НАН УкраїниIntroduction. Currently advances in different fields of biology and medicine accumulated large amount of high-throughput microarray datasets. It allows comparing, merging and analyzing such data in order to get more informative and statistically significant results. However, the process of cross-platform microarray data integration is complicated by different platform designs, that is the kind of probes used, the hybridization paradigm, the labeling and production methods. Such characteristics of microarray platforms should be considered when analyzing datasets from one study and even more when merging datasets.http://ojs.tdmu.edu.ua/index.php/here/article/view/6476
collection DOAJ
language English
format Article
sources DOAJ
author A. O. Frolova
V. S. Bondarenko
M. Yu. Obolenska
spellingShingle A. O. Frolova
V. S. Bondarenko
M. Yu. Obolenska
THE INFLUENCE OF CROSS-PLATFORM MICROARRAY DATA INTEGRATION ON GENE EXPRESSION VALUES IN HUMAN BREAST CANCER SAMPLES
Medična Informatika ta Inženerìâ
author_facet A. O. Frolova
V. S. Bondarenko
M. Yu. Obolenska
author_sort A. O. Frolova
title THE INFLUENCE OF CROSS-PLATFORM MICROARRAY DATA INTEGRATION ON GENE EXPRESSION VALUES IN HUMAN BREAST CANCER SAMPLES
title_short THE INFLUENCE OF CROSS-PLATFORM MICROARRAY DATA INTEGRATION ON GENE EXPRESSION VALUES IN HUMAN BREAST CANCER SAMPLES
title_full THE INFLUENCE OF CROSS-PLATFORM MICROARRAY DATA INTEGRATION ON GENE EXPRESSION VALUES IN HUMAN BREAST CANCER SAMPLES
title_fullStr THE INFLUENCE OF CROSS-PLATFORM MICROARRAY DATA INTEGRATION ON GENE EXPRESSION VALUES IN HUMAN BREAST CANCER SAMPLES
title_full_unstemmed THE INFLUENCE OF CROSS-PLATFORM MICROARRAY DATA INTEGRATION ON GENE EXPRESSION VALUES IN HUMAN BREAST CANCER SAMPLES
title_sort influence of cross-platform microarray data integration on gene expression values in human breast cancer samples
publisher Ukrmedknyha Publishing House
series Medična Informatika ta Inženerìâ
issn 1996-1960
1997-7468
publishDate 2016-08-01
description Introduction. Currently advances in different fields of biology and medicine accumulated large amount of high-throughput microarray datasets. It allows comparing, merging and analyzing such data in order to get more informative and statistically significant results. However, the process of cross-platform microarray data integration is complicated by different platform designs, that is the kind of probes used, the hybridization paradigm, the labeling and production methods. Such characteristics of microarray platforms should be considered when analyzing datasets from one study and even more when merging datasets.
url http://ojs.tdmu.edu.ua/index.php/here/article/view/6476
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