THE INFLUENCE OF CROSS-PLATFORM MICROARRAY DATA INTEGRATION ON GENE EXPRESSION VALUES IN HUMAN BREAST CANCER SAMPLES
Introduction. Currently advances in different fields of biology and medicine accumulated large amount of high-throughput microarray datasets. It allows comparing, merging and analyzing such data in order to get more informative and statistically significant results. However, the process of cross-pla...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Ukrmedknyha Publishing House
2016-08-01
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| Series: | Medična Informatika ta Inženerìâ |
| Online Access: | http://ojs.tdmu.edu.ua/index.php/here/article/view/6476 |
| Summary: | Introduction. Currently advances in different fields of biology and medicine accumulated large amount of high-throughput microarray datasets. It allows comparing, merging and analyzing such data in order to get more informative and statistically significant results. However, the process of cross-platform microarray data integration is complicated by different platform designs, that is the kind of probes used, the hybridization paradigm, the labeling and production methods. Such characteristics of microarray platforms should be considered when analyzing datasets from one study and even more when merging datasets. |
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| ISSN: | 1996-1960 1997-7468 |