Emerging Roles of 5-Lipoxygenase Phosphorylation in Inflammation and Cell Death

5-Lipoxygenase (ALOX5) is an iron-containing and nonheme dioxygenase that catalyzes the peroxidation of polyunsaturated fatty acids such as arachidonic acid. ALOX5 is the rate-limiting enzyme for the biosynthesis of leukotrienes, a family of proinflammatory lipid mediators derived from arachidonic a...

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Bibliographic Details
Main Authors: Qian-Yi Sun, Hong-Hao Zhou, Xiao-Yuan Mao
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2019/2749173