Knocking down Israa, the Zmiz1 intron-nested gene, unveils interrelated T cell activation functions in mouse

Knocking down Israa, the Zmiz1 intron-nested gene, unveils interrelated T cell activation functions in mouse

We previously reported Israa (immune-system-released activating agent), a novel gene nested in intron 6 of the mouse Zmiz1 gene. Zmiz1 is involved in several functions such as fertility and T cell development and its knockout leads to non-viable embryos. We also reported ISRAA's expression in l...

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Bibliographic Details
Main Authors: Noureddine Ben Khalaf, Wedad Al-Mashoor, Azhar Saeed, Wassim Raslan, Halla Bakheit, Ameera Abdulhadi, Ammar Marouani, Safa Taha, Moiz Bakhiet, M. Dahmani Fathallah
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Biochemistry and Biophysics Reports
Subjects:
T cell activation
Nested gene
Knock-out
Fyn
Elf-1
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580821001953

Internet

http://www.sciencedirect.com/science/article/pii/S2405580821001953

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