Repeated Intravenous Thrombolysis in Patients with Recurrent Ischemic Stroke in the Vertebrobasilar Territory

• Main Authors: David Černík, Dušan Ospalík, Daniel Šaňák, Filip Cihlář
• Format: Article
• Language: English
• Published: Karger Publishers 2021-07-01
• Series: Case Reports in Neurology
• Subjects: repeated intravenous thrombolysis; ischemic stroke; basilar artery occlusion; eptifibatide
• Online Access: https://www.karger.com/Article/FullText/518193

Acute ischemic vertebrobasilar stroke (AIVBS) is usually associated with poor outcome and prognosis and in case of basilar artery occlusion (BAO) with high mortality. Intravenous thrombolysis (IVT), as a standard recanalization therapy of acute ischemic stroke (IS) within first 4.5 h, can be administrated beyond this therapeutic time window in case of symptomatic BAO. Repeated IVT is generally contraindicated in case of early recurrent IS, despite a risk of poor outcome or death after recurrent IS. The aim was to present 2 cases of repeated IVT for recurrent AIVBS and discuss specific situations where repeated IVT may be considered. Up to now, repeated IVT has been reported only in recurrent stroke in anterior circulation.