Hairy Projections on Non Hairy Cells- A Case Report
Adult T-Cell Leukaemia/Lymphoma (ATLL) is a mature T-cell neoplasm. It is caused by human retrovirus Human T-cell Lymphotropic Virus Type 1(HTLV-1). The neoplastic cells after monoclonal integration begin to express T-cell associated antigens namely CD2, CD3 and CD5. These leukaemic cells are high...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2021-08-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/15289/49864_CE[Ra1]_F[SK]_PF1(MG_SHU)_PFA(MG_KM)_PN(KM).pdf |
| Summary: | Adult T-Cell Leukaemia/Lymphoma (ATLL) is a mature T-cell neoplasm. It is caused by human retrovirus Human T-cell Lymphotropic
Virus Type 1(HTLV-1). The neoplastic cells after monoclonal integration begin to express T-cell associated antigens namely CD2,
CD3 and CD5. These leukaemic cells are highly pleomorphic in light microscopic appearance and also they have a highly variable
clinical presentation ranging from acute to lymphomatous to chronic to smouldering. There is a chance of missed or miss diagnosis
due to their morphological and clinical heterogeneity and specialised test like immunophenotyping or flow cytometry is essential
for exact categorisation. Authors hereby, report a case of 45-year-old female patient suffering from ATLL whose peripheral smear
showed leukaemic cells with unusual hairy projections resembling hairy cell leukaemia posing diagnostic dilemma. |
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| ISSN: | 2249-782X 0973-709X |