Identification of a novel deletion mutation in DPY19L2 from an infertile patient with globozoospermia: a case report

Identification of a novel deletion mutation in DPY19L2 from an infertile patient with globozoospermia: a case report

Abstract Background Male infertility is an increasing medical concern worldwide. In most cases, genetic factors are considered as the main cause of the disease. Globozoospermia (MIM102530) (also known as round-headed sperm) is a rare and severe malformed spermatospermia caused by acrosome deficiency...

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Bibliographic Details
Main Authors: You-zhu Li, Rong-feng Wu, Xing-shen Zhu, Wen-sheng Liu, Yuan-yuan Ye, Zhong-xian Lu, Na Li
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Molecular Cytogenetics
Subjects:
Case report
Globozoospermia
Gene mutations
CNV sequencing
DPY19L2
Online Access:http://link.springer.com/article/10.1186/s13039-020-00495-1

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http://link.springer.com/article/10.1186/s13039-020-00495-1

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