The Origins and Generation of Cancer-Associated Mesenchymal Stromal Cells: An Innovative Therapeutic Target for Solid Tumors

The Origins and Generation of Cancer-Associated Mesenchymal Stromal Cells: An Innovative Therapeutic Target for Solid Tumors

Cancer-associated mesenchymal stromal cells (CA-MSCs) have been isolated from various types of tumors and are characterized by their vigorous pro-tumorigenic functions. However, very little is known about the origins and generating process of CA-MSCs, which may facilitate the identification of bioma...

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Bibliographic Details
Main Authors: Wei Li, Jin Yang, Ping Zheng, Haining Li, Shaolin Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Oncology
Subjects:
mesenchymal stromal cells
solid tumor
tumor microenvironment
malignant transition
generating process
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.723707/full

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