Human Tendon Stem/Progenitor Cell Features and Functionality Are Highly Influenced by in vitro Culture Conditions

Human Tendon Stem/Progenitor Cell Features and Functionality Are Highly Influenced by in vitro Culture Conditions

Our understanding of tendon biology continues to evolve, thus leading to opportunities for developing novel, evidence-based effective therapies for the treatment of tendon disorders. Implementing the knowledge of tendon stem/progenitor cells (TSPCs) and assessing their potential in enhancing tendon...

Full description

Bibliographic Details
Main Authors:	Carlotta Perucca Orfei, Annie C Bowles, Dimitrios Kouroupis, Melissa A Willman, Enrico Ragni, Lee D Kaplan, Thomas M Best, Diego Correa, Laura de Girolamo
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-09-01
Series:	Frontiers in Bioengineering and Biotechnology
Subjects:	tendinopathy Tendon Stem/Progenitor cells culture density inflammation immunomodulation substance P
Online Access:	https://www.frontiersin.org/articles/10.3389/fbioe.2021.711964/full

Similar Items

Reliable Reference Genes for Gene Expression Assessment in Tendon-Derived Cells under Inflammatory and Pro-Fibrotic/Healing Stimuli
by: Enrico Ragni, et al.
Published: (2019-10-01)

Tendon vasculature in health and disease.
by: Herbert eTempfer, et al.
Published: (2015-11-01)

Human Diseased Articular Cartilage Contains a Mesenchymal Stem Cell-Like Population of Chondroprogenitors with Strong Immunomodulatory Responses
by: Paola De Luca, et al.
Published: (2019-03-01)

Treatment with Human Amniotic Suspension Allograft Improves Tendon Healing in a Rat Model of Collagenase-Induced Tendinopathy
by: Laura de Girolamo, et al.
Published: (2019-11-01)

An investigation of tendon pain and failed tendon healing in a calcific tendinopathy rat model.
Published: (2009)

Pulsed electromagnetic fields improve the healing process of Achilles tendinopathy: a pilot study in a rat model
by: Carlotta Perucca Orfei, et al.
Published: (2020-09-01)

Spectrum of Tendon Pathologies: Triggers, Trails and End-State
by: Sara Steinmann, et al.
Published: (2020-01-01)

The plantaris tendon in relation to the Achilles tendon in midportion Achilles tendinopathy : studies on morphology, innervation and signalling substances
by: Spang, Christoph
Published: (2015)

Bilateral gluteus medius and minimus calcific tendonitis in a patient with previous bilateral calcific tendonitis of the shoulder: A case report
by: Mostafa Ellatif, MBBS, iBSc, FRCR, et al.
Published: (2021-11-01)

Sustained Exposure of Substance P Causes Tendinopathy
by: Seo Yoon Oh, et al.
Published: (2020-11-01)

Advances of stem cell based-therapeutic approaches for tendon repair
by: Lidi Liu, et al.
Published: (2017-04-01)

Changes in histoanatomical distribution of types I, III and V collagen promote adaptative remodeling in posterior tibial tendon rupture
by: Érika Satomi, et al.
Published: (2008-01-01)

Acute Achilles tendon rupture after levofloxacin in a patient with giant cell arteritis
by: Małgorzata Stasiek, et al.
Published: (2019-12-01)

Evidence Supporting Intralesional Stem Cell Therapy to Improve Equine Flexor Tendon Healing
by: Sushmitha Durgam, et al.
Published: (2017-01-01)

Fibrochondrogenic differentiation potential of tendon-derived stem/progenitor cells from human patellar tendon
by: Shengnan Qin, et al.
Published: (2020-05-01)

Extensive Ossification of the Achilles Tendon with and without Acute Fracture: A Scoping Review
by: Daniel Sullivan, et al.
Published: (2021-08-01)

The expression of substance P and calcitonin gene-related peptide is associated with the severity of tendon degeneration in lateral epicondylitis
by: Soo-Hong Han, et al.
Published: (2021-02-01)

Aromatase Inhibitor-Associated Tendinopathy and Muscle Tendon Rupture: Report of Three Cases of This Exceedingly Rare Adverse Event
by: Nikolaos Mitsimponas, et al.
Published: (2018-08-01)

Reparative and Maladaptive Inflammation in Tendon Healing
by: Varun Arvind, et al.
Published: (2021-07-01)

Ultrasound elastography: compression elastography and shear-wave elastography in the assessment of tendon injury
by: Rui Prado-Costa, et al.
Published: (2018-08-01)

Muscle and Tendon Adaptation in Adolescence: Elite Volleyball Athletes Compared to Untrained Boys and Girls
by: Falk Mersmann, et al.
Published: (2017-06-01)

Tendon Stem/Progenitor Cell Subpopulations and Their Implications in Tendon Biology
by: Zizhan Huang, et al.
Published: (2021-02-01)

The advances in diagnostic modalities of disorders of the long head of the biceps tendon – review
by: Maciej Gagat, et al.
Published: (2021-03-01)

A Functional High-Load Exercise Intervention for the Patellar Tendon Reduces Tendon Pain Prevalence During a Competitive Season in Adolescent Handball Players
by: Falk Mersmann, et al.
Published: (2021-03-01)

Management of Achilles and patellar tendinopathy: what we know, what we can do
by: Rocco Aicale, et al.
Published: (2020-09-01)

PEDF-derived peptide promotes tendon regeneration through its mitogenic effect on tendon stem/progenitor cells
by: Tsung-Chuan Ho, et al.
Published: (2019-01-01)

Imbalances in the Development of Muscle and Tendon as Risk Factor for Tendinopathies in Youth Athletes: A Review of Current Evidence and Concepts of Prevention
by: Falk Mersmann, et al.
Published: (2017-12-01)

Neovascularization in Meniscus and Tendon Pathology as a Potential Mechanism in Regenerative Therapies: Special Reference to Platelet-Rich Plasma Treatment
by: Dawid Szwedowski, et al.
Published: (2021-09-01)

MRI of the Achilles tendon – a comprehensive pictorial review. Part two
by: Pawel Szaro, et al.
Published: (2021-01-01)

Neuropeptide and catecholamine effects on tenocytes in tendinosis development : studies on two model systems with focus on proliferation and apoptosis
by: Backman, Ludvig
Published: (2013)

Tendinopathy: injury, repair, and current exploration
by: Lipman K, et al.
Published: (2018-03-01)

An Objective Measure of Patellar Tendon Thickness Based on Ultrasonography and MRI in University Athletes
by: Yusuke Nishida, et al.
Published: (2021-09-01)

The Roles of MicroRNAs in Tendon Healing and Regeneration
by: Lingli Ding, et al.
Published: (2021-07-01)

Evaluation of Autologous Protein Solution Injection for Treatment of Superficial Digital Flexor Tendonitis in an Equine Model
by: Angela M. Gaesser, et al.
Published: (2021-07-01)

Glutamate signaling through the NMDA receptor reduces the expression of scleraxis in plantaris tendon derived cells
by: Christoph Spang, et al.
Published: (2017-05-01)

The human Achilles tendon : innervation and intratendinous production of nerve signal substances - of importance in understanding the processes of Achilles tendinosis
by: Bjur, Dennis
Published: (2010)

Molecular Mechanisms of Fetal Tendon Regeneration Versus Adult Fibrous Repair
by: Iris Ribitsch, et al.
Published: (2021-05-01)

Higher BMP Expression in Tendon Stem/Progenitor Cells Contributes to the Increased Heterotopic Ossification in Achilles Tendon With Aging
by: Guangchun Dai, et al.
Published: (2020-09-01)

Impaired function of tendon-derived stem cells in experimental diabetes mellitus rat tendons: implications for cellular mechanism of diabetic tendon disorder
by: Liu SHI, et al.
Published: (2019-01-01)

Are we over-treating biceps tendon disorders?
by: Ali Tufan Pehlivan, et al.
Published: (2017-09-01)

Cannot write session to /tmp/vufind_sessions/sess_k2qjautvq7pn0ovhsoh6493bs0