COVID-19 Infection among People with HIV/AIDS in Africa: Knowledge Gaps, Public Health Preparedness and Research Priorities

The emergence of novel virus SARS-CoV-2 that causes COVID-19 has complicated Africa’s public health challenges, especially with the pre-existing epidemics such as HIV/AIDS. We highlight the known evidence related to COVID-19 infections among people with HIV (PWH) with specific reference to Africa....

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Main Authors: Ekere James Essien, Osaro Mgbere, Sorochi Iloanusi, Susan V. Abughosh
Format: Article
Language:English
Published: Global Health and Education Projects, Inc. 2021-03-01
Series:International Journal of Maternal and Child Health and AIDS
Online Access:https://mchandaids.org/index.php/IJMA/article/view/461
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spelling doaj-dec2dc00081b451ea32a6d11360bff4d2021-09-02T16:58:27ZengGlobal Health and Education Projects, Inc.International Journal of Maternal and Child Health and AIDS2161-86742161-864X2021-03-0110110.21106/ijma.461COVID-19 Infection among People with HIV/AIDS in Africa: Knowledge Gaps, Public Health Preparedness and Research PrioritiesEkere James Essien0Osaro Mgbere1Sorochi Iloanusi2Susan V. Abughosh3Institute of Community Health, University of Houston College of Pharmacy, Houston, Texas, USA; Department of Pharmaceutical Health Outcomes and Policy, University of Houston College of Pharmacy, Houston, Texas, USA; Department of Health Promotion and Behavioral Sciences, University of Texas School of Public Health, Houston, Texas, USAInstitute of Community Health, University of Houston College of Pharmacy, Houston, Texas, USA; Department of Pharmaceutical Health Outcomes and Policy, University of Houston College of Pharmacy, Houston, Texas, USA; Disease Prevention and Control Division, Houston Health Department, Houston, Texas, USADepartment of Pharmaceutical Health Outcomes and Policy, University of Houston College of Pharmacy, Houston, Texas, USAInstitute of Community Health, University of Houston College of Pharmacy, Houston, Texas, USA; Department of Pharmaceutical Health Outcomes and Policy, University of Houston College of Pharmacy, Houston, Texas, USA The emergence of novel virus SARS-CoV-2 that causes COVID-19 has complicated Africa’s public health challenges, especially with the pre-existing epidemics such as HIV/AIDS. We highlight the known evidence related to COVID-19 infections among people with HIV (PWH) with specific reference to Africa. The knowledge gaps, level of public health preparedness and the potential research priorities are also outlined. Although the epidemiology and clinical course of COVID-19 in HIV patients are evolving, existing evidence indicate that the disease outcomes are comparable to that of the general population. However, PWH with low CD4 cell counts may have worse outcomes than individuals with restored immunity, whereas old age and co-morbidities such as obesity, hypertension and diabetes can further increase their overall risk. While there may be slight disruption of HIV service delivery in selected African countries, the resilience and resourcefulness of others have helped to sustain HIV service delivery and enhanced the level of public health preparedness and fight against the pandemic. The paucity of data and research studies on HIV-COVID-19 coinfection in Africa, call for concerted efforts to address these limitations. Keywords: • COVID-19 • SARS-CoV-2 • HIV • PWH • Public Health • Research • Africa   Copyright © 2021 Essien, et al. Published by Global Health and Education Projects, Inc. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in this journal, is properly cited. https://mchandaids.org/index.php/IJMA/article/view/461
collection DOAJ
language English
format Article
sources DOAJ
author Ekere James Essien
Osaro Mgbere
Sorochi Iloanusi
Susan V. Abughosh
spellingShingle Ekere James Essien
Osaro Mgbere
Sorochi Iloanusi
Susan V. Abughosh
COVID-19 Infection among People with HIV/AIDS in Africa: Knowledge Gaps, Public Health Preparedness and Research Priorities
International Journal of Maternal and Child Health and AIDS
author_facet Ekere James Essien
Osaro Mgbere
Sorochi Iloanusi
Susan V. Abughosh
author_sort Ekere James Essien
title COVID-19 Infection among People with HIV/AIDS in Africa: Knowledge Gaps, Public Health Preparedness and Research Priorities
title_short COVID-19 Infection among People with HIV/AIDS in Africa: Knowledge Gaps, Public Health Preparedness and Research Priorities
title_full COVID-19 Infection among People with HIV/AIDS in Africa: Knowledge Gaps, Public Health Preparedness and Research Priorities
title_fullStr COVID-19 Infection among People with HIV/AIDS in Africa: Knowledge Gaps, Public Health Preparedness and Research Priorities
title_full_unstemmed COVID-19 Infection among People with HIV/AIDS in Africa: Knowledge Gaps, Public Health Preparedness and Research Priorities
title_sort covid-19 infection among people with hiv/aids in africa: knowledge gaps, public health preparedness and research priorities
publisher Global Health and Education Projects, Inc.
series International Journal of Maternal and Child Health and AIDS
issn 2161-8674
2161-864X
publishDate 2021-03-01
description The emergence of novel virus SARS-CoV-2 that causes COVID-19 has complicated Africa’s public health challenges, especially with the pre-existing epidemics such as HIV/AIDS. We highlight the known evidence related to COVID-19 infections among people with HIV (PWH) with specific reference to Africa. The knowledge gaps, level of public health preparedness and the potential research priorities are also outlined. Although the epidemiology and clinical course of COVID-19 in HIV patients are evolving, existing evidence indicate that the disease outcomes are comparable to that of the general population. However, PWH with low CD4 cell counts may have worse outcomes than individuals with restored immunity, whereas old age and co-morbidities such as obesity, hypertension and diabetes can further increase their overall risk. While there may be slight disruption of HIV service delivery in selected African countries, the resilience and resourcefulness of others have helped to sustain HIV service delivery and enhanced the level of public health preparedness and fight against the pandemic. The paucity of data and research studies on HIV-COVID-19 coinfection in Africa, call for concerted efforts to address these limitations. Keywords: • COVID-19 • SARS-CoV-2 • HIV • PWH • Public Health • Research • Africa   Copyright © 2021 Essien, et al. Published by Global Health and Education Projects, Inc. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in this journal, is properly cited.
url https://mchandaids.org/index.php/IJMA/article/view/461
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