Abdominal Fat and Metabolic Health Markers but Not PNPLA3 Genotype Predicts Liver Fat Accumulation in Response to Excess Intake of Energy and Saturated Fat in Healthy Individuals

Abdominal Fat and Metabolic Health Markers but Not PNPLA3 Genotype Predicts Liver Fat Accumulation in Response to Excess Intake of Energy and Saturated Fat in Healthy Individuals

Background: Saturated fat (SFA) has consistently been shown to increase liver fat, but the response appears variable at the individual level. Phenotypic and genotypic characteristics have been demonstrated to modify the hypercholesterolemic effect of SFA but it is unclear which characteristics that...

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Bibliographic Details
Main Authors: Fredrik Rosqvist, Marju Orho-Melander, Joel Kullberg, David Iggman, Hans-Erik Johansson, Jonathan Cedernaes, Håkan Ahlström, Ulf Risérus
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Nutrition
Subjects:
liver fat
saturated fat
overfeeding
NAFLD
fatty acids
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2020.606004/full

Internet

https://www.frontiersin.org/articles/10.3389/fnut.2020.606004/full

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