"BreakThrough cancer Pain" biomolecular mechanisms
The BTcP is a transitory exacerbation of pain of moderate to high intensity, which occurs, either spontaneously or as a result of a trigger factor, in patients with pain basic maintained for most of the day or under control of mild . The pathophysiological mechanisms underlying the development and...
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| Format: | Article |
| Language: | English |
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Publiediting
2014-11-01
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| Series: | Pathos |
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| Online Access: | http://www.pathos-journal.com/page_79.html |
| Summary: | The BTcP is a transitory exacerbation of pain of moderate to high intensity, which occurs, either spontaneously or as a result of a trigger factor, in patients with pain basic maintained for most of the day or under control of mild .
The pathophysiological mechanisms underlying the development and maintenance of this type of pain seem to depend on several factors including an increase in the activity of the receptors TRPV1, central sensitization, activation of Glia etc.
To better manage the disease can interfere with rapid analgesia of short duration that best overlaps the temporal characteristics of BTcP.
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| ISSN: | 1593-2354 1593-2354 |