Knock out of specific maternal vitellogenins in zebrafish (Danio rerio) evokes vital changes in egg proteomic profiles that resemble the phenotype of poor quality eggs

Knock out of specific maternal vitellogenins in zebrafish (Danio rerio) evokes vital changes in egg proteomic profiles that resemble the phenotype of poor quality eggs

Abstract Background We previously reported the results of CRISPR/Cas9 knock-out (KO) of type-I and type-III vitellogenins (Vtgs) in zebrafish, which provided the first experimental evidence on essentiality and disparate functioning of Vtgs at different stages during early development. However, the s...

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Bibliographic Details
Main Authors: Ozlem Yilmaz, Amelie Patinote, Emmanuelle Com, Charles Pineau, Julien Bobe
Format: Article
Language:English
Published: BMC 2021-04-01
Series:BMC Genomics
Subjects:
Zebrafish
Vitellogenin
Knock-out
CRISPR/Cas9
Proteomics
LC-MS/MS
Online Access:https://doi.org/10.1186/s12864-021-07606-1

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