A Role for Syntaxin 3 in the secretion of IL-6 from Dendritic Cells following activation of Toll-like Receptors

A Role for Syntaxin 3 in the secretion of IL-6 from Dendritic Cells following activation of Toll-like Receptors

The role of dendritic cells (DCs) in directing the immune response is due in part to their capacity to produce a range of cytokines. Importantly, DCs are a source of cytokines which can promote T cell survival and T helper cell differentiation. While it has become evident that soluble-N-ethylmaleimi...

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Bibliographic Details
Main Authors: Laura E Collins, Joseph eDeCourcey, Keith D Rochfort, Maja eKristek, Christine E Loscher
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-01-01
Series:Frontiers in Immunology
Subjects:
Dendritic Cells
IL-6
SNAREs
MIP-1α
STX3
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00691/full

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