Liposome-Encapsulated Morphine Affords a Prolonged Analgesia While Facilitating Extinction of Reward and Aversive Memories

Liposome-Encapsulated Morphine Affords a Prolonged Analgesia While Facilitating Extinction of Reward and Aversive Memories

Morphine is thoroughly used for pain control; however, it has a high addictive potential. Opioid liposome formulations produce controlled drug release and have been thoroughly tested for pain treatment although their role in addiction is still unknown. This study investigated the effects of free mor...

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Bibliographic Details
Main Authors: Victoria Gómez-Murcia, Bruno Ribeiro Do Couto, Juan C. Gómez-Fernández, María V. Milanés, María L. Laorden, Pilar Almela
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Pharmacology
Subjects:
liposomes (SUV, LUV)
morphine
analgesia
reward memory
aversive memory extinction
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01082/full

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