Therapeutic potential of boosting NAD+ in aging and age-related diseases

Therapeutic potential of boosting NAD+ in aging and age-related diseases

Nicotinamide adenine dinucleotide (NAD+) is an essential cofactor in all living cells that is involved in fundamental biological processes. NAD+ depletion has been associated with hallmarks of aging and may underlie a wide-range of age-related diseases, such as metabolic disorders, cancer and neurod...

Full description

Bibliographic Details
Main Authors:	Yahyah Aman, Yumin Qiu, Jun Tao, Evandro F. Fang
Format:	Article
Language:	English
Published:	KeAi Communications Co., Ltd. 2018-01-01
Series:	Translational Medicine of Aging
Online Access:	http://www.sciencedirect.com/science/article/pii/S2468501118300063

Similar Items

Potential Therapeutic Benefit of NAD<sup>+</sup> Supplementation for Glaucoma and Age-Related Macular Degeneration
by: Gloria Cimaglia, et al.
Published: (2020-09-01)

Targeting on the NAD+‐mitophagy axis to treat cardiovascular disease
by: Evandro F. Fang, et al.
Published: (2020-09-01)

NAD+ and sirtuins in aging and disease
by: Imai, Shin-ichiro, et al.
Published: (2017)

NAD+ augmentation restores mitophagy and limits accelerated aging in Werner syndrome
by: Evandro F. Fang, et al.
Published: (2019-11-01)

Investigating mechanisms of pain in Alzheimer's disease
by: Aman, Yahyah
Published: (2018)

Potential therapeutic target for aging and age-related neurodegenerative diseases: the role of acid sphingomyelinase
by: Min Hee Park, et al.
Published: (2020-03-01)

Tolerance to NADH/NAD+ imbalance anticipates aging and anti-aging interventions
by: Alvar J. Alonso-Lavin, et al.
Published: (2021-07-01)

Boosting NAD+ with a small molecule that activates NAMPT
by: Stephen J. Gardell, et al.
Published: (2019-07-01)

Therapeutic Potential of Quercetin to Alleviate Endothelial Dysfunction in Age-Related Cardiovascular Diseases
by: Olina Dagher, et al.
Published: (2021-03-01)

Effect of NAD+ boosting on kidney ischemia-reperfusion injury.
by: Marya Morevati, et al.
Published: (2021-01-01)

NAD+ biosynthesis, aging, and disease [version 1; referees: 2 approved]
by: Sean Johnson, et al.
Published: (2018-02-01)

New Insights for Cellular and Molecular Mechanisms of Aging and Aging-Related Diseases: Herbal Medicine as Potential Therapeutic Approach
by: Yanfei Liu, et al.
Published: (2019-01-01)

A need for NAD+ in muscle development, homeostasis, and aging
by: Michelle F. Goody, et al.
Published: (2018-03-01)

Influence of NAD+ as an ageing-related immunomodulator on COVID 19 infection: A hypothesis
by: Huda M. Omran, et al.
Published: (2020-09-01)

Complement System and Potential Therapeutics in Age-Related Macular Degeneration
by: Young Gun Park, et al.
Published: (2021-06-01)

Therapeutic potential of eccentric exercises for age-related muscle atrophy
by: Jae-Young Lim
Published: (2016-09-01)

Potential Therapeutic Candidates for Age-Related Macular Degeneration (AMD)
by: Sonali Nashine
Published: (2021-09-01)

NAD Metabolism in Cancer Therapeutics
by: Keisuke Yaku, et al.
Published: (2018-12-01)

The Role of Saikosaponins in Therapeutic Strategies for Age-Related Diseases
by: Byeong Mo Kim
Published: (2018-01-01)

Implications of NAD+ Metabolism in the Aging Retina and Retinal Degeneration
by: Ravirajsinh N. Jadeja, et al.
Published: (2020-01-01)

The Circadian NAD+ Metabolism: Impact on Chromatin Remodeling and Aging
by: Yasukazu Nakahata, et al.
Published: (2016-01-01)

Therapeutic potential of translocator protein ligands for age-related macular degeneration
by: Xing Li, et al.
Published: (2022-01-01)

Novel update of interventional strategies of vascular aging in humans
by: Yumin Qiu, et al.
Published: (2020-09-01)

Therapeutic Potential and Recent Advances of Curcumin in the Treatment of Aging-Associated Diseases
by: Sathish Sundar Dhilip Kumar, et al.
Published: (2018-04-01)

Clinical Evidence for Targeting NAD Therapeutically
by: Dina Radenkovic, et al.
Published: (2020-09-01)

Face Age Classification using Boosting
by: Yen-Yi Wu, et al.
Published: (2011)

NAD+ Repletion Rescues Female Fertility during Reproductive Aging
by: Michael J. Bertoldo, et al.
Published: (2020-02-01)

It takes two to tango: NAD+ and sirtuins in aging/longevity control
by: Imai, Shin-ichiro, et al.
Published: (2018)

NAD + supplementation rejuvenates aged gut adult stem cells
by: Igarashi, Masaki, et al.
Published: (2020)

Age related changes in NAD+ metabolism oxidative stress and Sirt1 activity in wistar rats.
by: Nady Braidy, et al.
Published: (2011-04-01)

NAD+ in Alzheimer’s Disease: Molecular Mechanisms and Systematic Therapeutic Evidence Obtained in vivo
by: Xinshi Wang, et al.
Published: (2021-08-01)

Hormone Replacement Therapy and Aging: A Potential Therapeutic Approach for Age-Related Oxidative Stress and Cardiac Remodeling
by: Renáta Szabó, et al.
Published: (2021-01-01)

Therapeutic Potential of HUMSCs in Female Reproductive Aging
by: Qiaojuan Mei, et al.
Published: (2021-05-01)

Complement Inhibitors in Age-Related Macular Degeneration: A Potential Therapeutic Option
by: Shuqi Qin, et al.
Published: (2021-01-01)

Central intracrine DHEA synthesis in ageing-related neuroinflammation and neurodegeneration: therapeutic potential?
by: Y S L Powrie, et al.
Published: (2018-10-01)

Potential Therapeutic Effects of Lipoic Acid on Memory Deficits Related to Aging and Neurodegeneration
by: Patrícia Molz, et al.
Published: (2017-12-01)

mTORC Inhibitors as Broad-Spectrum Therapeutics for Age-Related Diseases
by: Hannah E. Walters, et al.
Published: (2018-08-01)

Measuring Age Discrimination at Work: Spanish Adaptation and Preliminary Validation of the Nordic Age Discrimination Scale (NADS)
by: Patricia Carral, et al.
Published: (2019-04-01)

Age-associated changes in oxidative stress and NAD+ metabolism in human tissue.
by: Hassina Massudi, et al.
Published: (2012-01-01)

Changes in oxidative damage, inflammation and [NAD(H)] with age in cerebrospinal fluid.
by: Jade Guest, et al.
Published: (2014-01-01)