Loss of abdominal muscle in Pitx2 mutants associated with altered axial specification of lateral plate mesoderm.

Sequence specific transcription factors (SSTFs) combinatorially define cell types during development by forming recursively linked network kernels. Pitx2 expression begins during gastrulation, together with Hox genes, and becomes localized to the abdominal lateral plate mesoderm (LPM) before the ons...

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Bibliographic Details
Main Authors: Diana Eng, Hsiao-Yen Ma, Jun Xu, Hung-Ping Shih, Michael K Gross, Chrissa Kioussi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3409154?pdf=render