Characteristics of HIV-infected women and factors associated with HCV seropositivity in the Republic of Georgia

• Main Authors: Smith Perry F, McNutt Louise-Anne, Chkhartishvili Nikoloz, Tsertsvadze Tengiz
• Format: Article
• Language: English
• Published: BMC 2011-07-01
• Series: AIDS Research and Therapy
• Online Access: http://www.aidsrestherapy.com/content/8/1/25

<p>Abstract</p> <p>Background</p> <p>The aim of this study was to describe the extent of the HIV epidemic among women in the Republic of Georgia and to identify factors associated with HCV co-infection in this population.</p> <p>Findings</p> <p>All women aged ≥18 years who were diagnosed with HIV between 1989 and 2006 were identified through the National HIV/AIDS surveillance database. Medical records were reviewed for demographic characteristics, risk factors and HCV serostatus. A total of 249 women were identified. Only 4% declared injection drug use (IDU); sex work was reported by 9%. Substantial risk factors were identified among the women's sexual partners, nearly 69% of whom were IDUs, 84% were HIV positive and 66% HCV positive. Seventeen percent of women were seropositive for HCV. Factors significantly associated with HCV seropositivity in bivariate analyses among non-IDU women were partner IDU+ [Prevalence ratio (PR): 4.5 (95% CI: 1.4, 14.2)], and partner HCV+ [PR: 7.2 (95% CI: 1.8, 29.5)].</p> <p>Conclusions</p> <p>The HIV epidemic in the Republic of Georgia is closely tied to the IDU community. Evidence-based interventions targeting IDU and partners of IDU are urgently required to halt the spread of the HIV epidemic in the country.</p>