Structure-Activity Relationship Studies of N- and C-Terminally Modified Secretin Analogs for the Human Secretin Receptor.

Structure-Activity Relationship Studies of N- and C-Terminally Modified Secretin Analogs for the Human Secretin Receptor.

The pleiotropic role of human secretin (hSCT) validates its potential use as a therapeutic agent. Nevertheless, the structure of secretin in complex with its receptor is necessary to develop a suitable therapeutic agent. Therefore, in an effort to design a three-dimensional virtual homology model an...

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Bibliographic Details
Main Authors: Kailash Singh, Vijayalakshmi Senthil, Aloysius Wilfred Raj Arokiaraj, Jérôme Leprince, Benjamin Lefranc, David Vaudry, Ahmed A Allam, Jamaan Ajarem, Billy K C Chow
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4773067?pdf=render

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