R-848 triggers the expression of TLR7/8 and suppresses HIV replication in monocytes

<p>Abstract</p> <p>Background</p> <p>Toll-like receptors (TLR) 7 and 8 are important in single-stranded viral RNA recognition and may play a role in HIV infection and disease progression. We analyzed TLR7/8 expression and signaling in monocytes from HIV-infected and uni...

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Bibliographic Details
Main Authors: Nian Hua, Geng Wen-Qing, Cui Hua-Lu, Bao Ming-jia, Zhang Zi-ning, Zhang Min, Pan Ying, Hu Qing-Hai, Shang Hong
Format: Article
Language:English
Published: BMC 2012-01-01
Series:BMC Infectious Diseases
Subjects:
HIV
Online Access:http://www.biomedcentral.com/1471-2334/12/5