| Summary: | The therapy of the retina vasculitis is very complex. The basic therapeuticprinciple is to find a balance between the medicament toxicity and the seriousness ofthe retina disease. In easy forms of the disease, with a good seeing sharpness, it issufficient to observe a patient with no therapy at ali. For serious diseases themedicaments to be chosen are corticosteroids. Tf there is no favorable response to thecorticosteroid therapy, in bilateral serious forms of the retina vasculitis and especiallyin the Behchet disease, a therapy with cytostatics is applied. The most frequently usedare cyclophosphamide and chlorambucil. In the last few years s highly-selectiveimmunosuppressive cyclosporine A in small doses is used combined withcorticosteroids. A new approach to suppressing the auto-aggressive Ag-specific Tcellsand their pro-inflammatory products implies the use of a new generation of immunosuppressive medicaments such as tacrolimus (FK 506) and T-cell specificantimetabolites. More recently the desensibilization by the retina S-antigen has beenused in the therapy of the retina vasculitis.
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