Plasma phospholipid transfer activity is essential for increased atherogenesis in PLTP transgenic mice: a mutation-inactivation study

Plasma phospholipid transfer activity is essential for increased atherogenesis in PLTP transgenic mice: a mutation-inactivation study

Plasma phospholipid transfer protein (PLTP) interacts with HDL particles and facilitates the transfer of phospholipids from triglyceride (TG)-rich lipoproteins to HDL. Overexpressing human PLTP in mice increases the susceptibility to atherosclerosis. In human plasma, high-active and low-active forms...

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Bibliographic Details
Main Authors: Hannelore Samyn, Matthijs Moerland, Teus van Gent, Rien van Haperen, Jari Metso, Frank Grosveld, Matti Jauhiainen, Arie van Tol, Rini de Crom
Format: Article
Language:English
Published: Elsevier 2008-12-01
Series:Journal of Lipid Research
Subjects:
phospholipid transfer protein
lipoproteins
atherosclerosis
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752034582X

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http://www.sciencedirect.com/science/article/pii/S002222752034582X

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