Nordihydroguaiaretic acid reduces secondary organ injury in septic rats after cecal ligation and puncture.

BACKGROUND:Nordihydroguaiaretic acid (NDGA) is a plant extract that has been shown to act as a free radical scavenger and pluripotent inhibitor of pro-inflammatory cytokines, two major cellular processes involved in the pathophysiology of sepsis. We investigated whether NDGA would improve markers of...

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Bibliographic Details
Main Authors: Michael E Zubrow, Susan S Margulies, Nadir Yehya
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0237613

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