Adjuvant Effect of Cationic Liposomes for Subunit Influenza Vaccine: Influence of Antigen Loading Method, Cholesterol and Immune Modulators

Adjuvant Effect of Cationic Liposomes for Subunit Influenza Vaccine: Influence of Antigen Loading Method, Cholesterol and Immune Modulators

Cationic liposomes are potential adjuvants for influenza vaccines. In a previous study we reported that among a panel of cationic liposomes loaded with influenza hemagglutinin (HA), DC-Chol:DPPC (1:1 molar ratio) liposomes induced the strongest immune response. However, it is not clear whether the c...

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Bibliographic Details
Main Authors: Alexander Kros, Wim Jiskoot, Abdelrahman Elsharkawy, Stefan Romeijn, Christophe Barnier-Quer
Format: Article
Language:English
Published: MDPI AG 2013-07-01
Series:Pharmaceutics
Subjects:
adjuvant
cationic liposomes
cholesterol
CpG
H3N2
hemagglutinin
imiquimod
immunogenicity
influenza
Online Access:http://www.mdpi.com/1999-4923/5/3/392

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