Permeability changes and effect of chemotherapy in brain adjacent to tumor in an experimental model of metastatic brain tumor from breast cancer

Permeability changes and effect of chemotherapy in brain adjacent to tumor in an experimental model of metastatic brain tumor from breast cancer

Abstract Background Brain tumor vasculature can be significantly compromised and leakier than that of normal brain blood vessels. Little is known if there are vascular permeability alterations in the brain adjacent to tumor (BAT). Changes in BAT permeability may also lead to increased drug permeatio...

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Bibliographic Details
Main Authors: Afroz S. Mohammad, Chris E. Adkins, Neal Shah, Rawaa Aljammal, Jessica I. G. Griffith, Rachel M. Tallman, Katherine L. Jarrell, Paul R. Lockman
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Cancer
Subjects:
Brain metastases
Fluorescent microscopy
Autoradiography
Astrocytosis
Chemotherapy
Online Access:http://link.springer.com/article/10.1186/s12885-018-5115-x

Internet

http://link.springer.com/article/10.1186/s12885-018-5115-x

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