Gene Transcription as a Therapeutic Target in Leukemia

Gene Transcription as a Therapeutic Target in Leukemia

Blood malignancies often arise from undifferentiated hematopoietic stem cells or partially differentiated stem-like cells. A tight balance of multipotency and differentiation, cell division, and quiescence underlying normal hematopoiesis requires a special program governed by the transcriptional mac...

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Bibliographic Details
Main Authors: Alvina I. Khamidullina, Ekaterina A. Varlamova, Nour Alhuda Hammoud, Margarita A. Yastrebova, Alexandra V. Bruter
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
transcription
leukemia
targeted antitumor therapy
cell death
drug design
Online Access:https://www.mdpi.com/1422-0067/22/14/7340

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