Sign of Leser-Trélat and Cutaneous T-Cell Lymphoma: A Rare Association

Sign of Leser-Trélat and Cutaneous T-Cell Lymphoma: A Rare Association

Sign of Leser-Trélat is a rare paraneoplastic cutaneous manifestation, characterized by the sudden appearance and rapid increase in size and number of seborrheic keratoses, accompanied by pruritus. Edmund Leser and Ulysse Trélat described this sign in 1890. Since their first description, their concl...

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Bibliographic Details
Main Authors: Raphaël André, Emmanuel Laffitte, Marem Abosaleh, Bégonia Cortès, Laurence Toutous-Trellu, Gürkan Kaya
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:Dermatopathology
Subjects:
T-cell lymphoma
Sign of Leser-Trélat
Seborrheic keratosis
Online Access:https://www.karger.com/Article/FullText/488982
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spelling doaj-de1c433a732f4fbcb752ba4d2e3feebd2021-01-02T04:44:08ZengMDPI AGDermatopathology2296-35292018-05-0152697310.1159/000488982488982Sign of Leser-Trélat and Cutaneous T-Cell Lymphoma: A Rare AssociationRaphaël AndréEmmanuel LaffitteMarem AbosalehBégonia CortèsLaurence Toutous-TrelluGürkan KayaSign of Leser-Trélat is a rare paraneoplastic cutaneous manifestation, characterized by the sudden appearance and rapid increase in size and number of seborrheic keratoses, accompanied by pruritus. Edmund Leser and Ulysse Trélat described this sign in 1890. Since their first description, their conclusions have been considered controversial and some authors assert the absence of a causal link. It seems to be frequently associated with solid tumors and in particular gastrointestinal cancer. Here, we describe a new case associated with a cutaneous T-cell lymphoma and a partial response to extracorporeal photopheresis.https://www.karger.com/Article/FullText/488982T-cell lymphomaSign of Leser-TrélatSeborrheic keratosis
collection DOAJ
language English
format Article
sources DOAJ
author Raphaël André
Emmanuel Laffitte
Marem Abosaleh
Bégonia Cortès
Laurence Toutous-Trellu
Gürkan Kaya
spellingShingle Raphaël André
Emmanuel Laffitte
Marem Abosaleh
Bégonia Cortès
Laurence Toutous-Trellu
Gürkan Kaya
Sign of Leser-Trélat and Cutaneous T-Cell Lymphoma: A Rare Association
Dermatopathology
T-cell lymphoma
Sign of Leser-Trélat
Seborrheic keratosis
author_facet Raphaël André
Emmanuel Laffitte
Marem Abosaleh
Bégonia Cortès
Laurence Toutous-Trellu
Gürkan Kaya
author_sort Raphaël André
title Sign of Leser-Trélat and Cutaneous T-Cell Lymphoma: A Rare Association
title_short Sign of Leser-Trélat and Cutaneous T-Cell Lymphoma: A Rare Association
title_full Sign of Leser-Trélat and Cutaneous T-Cell Lymphoma: A Rare Association
title_fullStr Sign of Leser-Trélat and Cutaneous T-Cell Lymphoma: A Rare Association
title_full_unstemmed Sign of Leser-Trélat and Cutaneous T-Cell Lymphoma: A Rare Association
title_sort sign of leser-trélat and cutaneous t-cell lymphoma: a rare association
publisher MDPI AG
series Dermatopathology
issn 2296-3529
publishDate 2018-05-01
description Sign of Leser-Trélat is a rare paraneoplastic cutaneous manifestation, characterized by the sudden appearance and rapid increase in size and number of seborrheic keratoses, accompanied by pruritus. Edmund Leser and Ulysse Trélat described this sign in 1890. Since their first description, their conclusions have been considered controversial and some authors assert the absence of a causal link. It seems to be frequently associated with solid tumors and in particular gastrointestinal cancer. Here, we describe a new case associated with a cutaneous T-cell lymphoma and a partial response to extracorporeal photopheresis.
topic T-cell lymphoma
Sign of Leser-Trélat
Seborrheic keratosis
url https://www.karger.com/Article/FullText/488982
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