Honokiol induces calpain-mediated glucose-regulated protein-94 cleavage and apoptosis in human gastric cancer cells and reduces tumor growth.
BACKGROUND: Honokiol, a small molecular weight natural product, has been shown to possess potent anti-neoplastic and anti-angiogenic properties. Its molecular mechanisms and the ability of anti-gastric cancer remain unknown. It has been shown that the anti-apoptotic function of the glucose-regulated...
Main Authors: | Meei Ling Sheu, Shing Hwa Liu, Keng Hsin Lan |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2007-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2034534?pdf=render |
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