Apigenin Attenuates the Allergic Reactions by Competitively Binding to ER With Estradiol

Apigenin Attenuates the Allergic Reactions by Competitively Binding to ER With Estradiol

Apigenin (API) is a natural phytoestrogen with properties including anti-inflammatory and other abilities. This study aims to 1) systematically validate that excessive estrogen exacerbates allergic reactions; 2) explore the anti-allergic effects and mechanisms of API. We conduct a survey of college...

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Bibliographic Details
Main Authors: Lu Yao, Zhuoyan Fan, Shiwen Han, Na Sun, Huilian Che
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Pharmacology
Subjects:
apigenin
estrogen receptor
MAPK signaling pathway
Th1/Th2 balance
allergic disease
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.01046/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.01046/full

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