Generation and characterization of an Nxf7 knockout mouse to study NXF5 deficiency in a patient with intellectual disability.

Generation and characterization of an Nxf7 knockout mouse to study NXF5 deficiency in a patient with intellectual disability.

Members of the Nuclear eXport Factor (NXF) family are involved in the export of mRNA from the nucleus to the cytoplasm, or hypothesized to play a role in transport of cytoplasmic mRNA. We previously reported on the loss of NXF5 in a male patient with a syndromic form of intellectual disability. To s...

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Bibliographic Details
Main Authors: Lieselot Vanmarsenille, Jelle Verbeeck, Stefanie Belet, Anton J Roebroek, Tom Van de Putte, Joke Nevelsteen, Zsuzsanna Callaerts-Vegh, Rudi D'Hooge, Peter Marynen, Guy Froyen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3652825?pdf=render

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