Cyanidin-3-O-β-glucoside and protocatechuic acid activate AMPK/mTOR/S6K pathway and improve glucose homeostasis in mice

Cyanidin-3-O-β-glucoside and protocatechuic acid activate AMPK/mTOR/S6K pathway and improve glucose homeostasis in mice

AMP-activated protein kinase (AMPK) activation is an established treatment for diabetes. Here the effects of anthocyanin extract from blood orange juice, i.e. cyanidin-3-O-β-glucoside (C3G) and its secondary metabolite protocatechuic acid (PCA), on AMPK signalling in murine hepatic cell line and in...

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Bibliographic Details
Main Authors: Veena Talagavadi, Paolo Rapisarda, Fabio Galvano, Piergiuseppe Pelicci, Marco Giorgio
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:Journal of Functional Foods
Subjects:
Blood oranges
Anthocyanin
AMPK
mTOR
Glucose homeostasis
Laboratory mice
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464615006118

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