Study on a two-component signal transduction system RimA1A2 that negatively regulates oxytetracycline biosynthesis in Streptomyces rimosus M4018

Study on a two-component signal transduction system RimA1A2 that negatively regulates oxytetracycline biosynthesis in Streptomyces rimosus M4018

Abstract Biosynthesis of secondary metabolites in actinobacteria is regulated by complex regulatory mechanisms on responding environmental changes. In this study, we have identified a two-component system (TCS) designated as RimA1A2 in the genome of Streptomyces rimosus M4018, with high homology to...

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Bibliographic Details
Main Authors: Hui Ni, Zhiqiang Xiong, Ali Mohsin, Meijin Guo, Hrvoje Petkovic, Ju Chu, Yingping Zhuang
Format: Article
Language:English
Published: SpringerOpen 2019-01-01
Series:Bioresources and Bioprocessing
Subjects:
RimA1A2
Oxytetracycline biosynthesis
Two-component regulatory system
Environmental stress
Streptomyces rimosus
Negative regulation
Online Access:http://link.springer.com/article/10.1186/s40643-019-0238-8

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