Modified lipoprotein-derived lipid particles accumulate in human stenotic aortic valves.
In aortic stenosis plasma lipoprotein-derived lipids accumulate in aortic valves. Here, we first compared the lipid compositions of stenotic aortic valves and atherosclerotic plaque cores. Both pathological tissues were found to be enriched in cholesteryl linoleate, a marker of extracellularly accum...
Main Authors: | Satu Lehti, Reijo Käkelä, Sohvi Hörkkö, Outi Kummu, Satu Helske-Suihko, Markku Kupari, Kalervo Werkkala, Petri T Kovanen, Katariina Oörni |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23762432/pdf/?tool=EBI |
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