EFFCT OF ZINGIBEN OFFICINALE PLANT AND H2O2 ON SOME PHYSIOLOGICAL , HISTOLOGICAL AND BIOCHEMICAL PARAMETERS IN LOCAL MALE RABBITS

• Main Authors: Muntaha Al– Kattan, Raja Al – Annaz, Iman Al– Sarrag
• Format: Article
• Language: Arabic
• Published: College of Agriculture 2007-03-01
• Series: Mesopotamia Journal of Agriculture
• Online Access: https://magrj.mosuljournals.com/article_26468_c6d9ab4fd76b19a4fc02836dc2afca6e.pdf

This study was conducted to investigate the protective effect of Zingiben Officinale against the H2O2 induced oxidative stress in local male rabbits 5 – 6 months old . Rabbits were divided into 4 groups 4 rabbits each . Zingiben officinale was used as capsules at a dose of 1000 mg / kg. B. wt . The rabbits were treated dialy for 28 days . Oxidative stress was determined through measuring the levels of glutathione GSH and malondialdehyde MDA in liver tissue and of ALT and AST enzymes levels . H2O2 treatment showed significant decrease in liver tissue MDA and a significant increase liver tissue GSH serum AST and ALT were significantly increase also the above changes indicate the ability of H2O2 (1 %) in the induction of oxidative stress in local male rabbits .The treatment with zingiben officinale showed the following results significant decrease in ALT and AST serum levels , also significant decrease in liver tissue MDA and significant increase in GSH level , significant decrease in liver fat % These results indicate the protective effect of ZingibenOfficinal against oxidative stress .