Unsupervised Analysis of Array Comparative Genomic Hybridization Data from Early-Onset Colorectal Cancer Reveals Equivalence with Molecular Classification and Phenotypes

Unsupervised Analysis of Array Comparative Genomic Hybridization Data from Early-Onset Colorectal Cancer Reveals Equivalence with Molecular Classification and Phenotypes

AIM: To investigate whether chromosomal instability (CIN) is associated with tumor phenotypes and/or with global genomic status based on MSI (microsatellite instability) and CIMP (CpG island methylator phenotype) in early-onset colorectal cancer (EOCRC). METHODS: Taking as a starting point our previ...

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Main Authors: María Arriba, Juan L. García, Daniel Rueda, Jessica Pérez, Lorena Brandariz, Oana A. Nutu, Laura Alonso, Yolanda Rodríguez, Miguel Urioste, Rogelio González-Sarmiento, José Perea
Format: Article
Language:English
Published: Elsevier 2017-01-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558616300902

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http://www.sciencedirect.com/science/article/pii/S1476558616300902

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