Comprehensive Cohort Analysis of Mutational Spectrum in Early Onset Breast Cancer Patients

Comprehensive Cohort Analysis of Mutational Spectrum in Early Onset Breast Cancer Patients

Early onset breast cancer (EOBC), diagnosed at age ~40 or younger, is associated with a poorer prognosis and higher mortality rate compared to breast cancer diagnosed at age 50 or older. EOBC poses a serious threat to public health and requires in-depth investigation. We studied a cohort comprising...

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Bibliographic Details
Main Authors: Mohit K. Midha, Yu-Feng Huang, Hsiao-Hsiang Yang, Tan-Chi Fan, Nai-Chuan Chang, Tzu-Han Chen, Yu-Tai Wang, Wen-Hung Kuo, King-Jen Chang, Chen-Yang Shen, Alice L. Yu, Kuo-Ping Chiu, Chien-Jen Chen
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cancers
Subjects:
early onset breast cancer (EOBC)
missense mutations
nonsynonymous mutations
somatic mutations
germline mutations
Online Access:https://www.mdpi.com/2072-6694/12/8/2089

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