Wound Complications after 2-Octyl Skin Closure Systems for Total Joint Arthroplasty

• Main Authors: A. Michalowitz, R. Comrie, C. Nicholas, M. Wagner, J. Kehoe
• Format: Article
• Language: English
• Published: Copernicus Publications 2020-04-01
• Series: Journal of Bone and Joint Infection
• Online Access: https://jbji.copernicus.org/articles/5/101/2020/jbji-5-101-2020.pdf

<p class="p p-first" id="__p2"><strong>Introduction</strong>: Total joint arthroplasty is projected to expand rapidly by 2030. With large numbers of patients undergoing TJA, the choice of incisional closure has come into question. We compared the 2-Ocyl cyanoacrylate closure system of Dermabond ® Prineo ® with Exofin Fusion ® to compare rates of adverse wound outcomes after total joint arthroplasty. Secondary outcome measures were age, sex, and medical comorbidities between groups.</p><p id="__p3"><strong>Methods</strong>: We retrospectively reviewed adverse wound outcomes with skin closure in TJA in 281 patients (160 Dermabond Prineo and 121 Exofin Fusion). Clinical charts were analyzed out to the 6-week post-op visit.</p><p id="__p4"><strong>Results</strong>: The rate of overall adverse superficial wound outcomes was similar between the two groups with Dermabond Prineo (N=20) and Exofin Fusion (N=19). The rate of cellulitis was significantly higher for Dermabond Prineo when compared to Exofin Fusion (P=0.033). No other significant differences were found for rate of superficial or deep wound complications or for secondary outcomes.</p><p class="p p-last" id="__p5"><strong>Conclusions</strong>: The two 2-octyl wound closure systems had similar adverse superficial wound complications. Except for Dermabond Prineo having a higher rate of post-operative cellulitis, there were no statistically significant differences for other superficial or deep adverse wound outcomes or secondary outcomes. A future randomized control trial or prospective cohort study is needed for a more robust analysis.</p>