Analytical validation of the Target Selector ctDNA platform featuring single copy detection sensitivity for clinically actionable EGFR, BRAF, and KRAS mutations.

Analytical validation of the Target Selector ctDNA platform featuring single copy detection sensitivity for clinically actionable EGFR, BRAF, and KRAS mutations.

<h4>Background</h4>Personalized medicine requires accurate molecular profiling for targeted therapy decisions. Insufficient tissue yield or tumor heterogeneity frequently limits the correct tissue biomarker determination. As a noninvasive complement to traditional tissue biopsies, liquid...

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Bibliographic Details
Main Authors: Jason C Poole, Shan-Fu Wu, Timothy T Lu, Cecile Rose T Vibat, Anh Pham, Errin Samuelsz, Manisha Patel, Jeffrey Chen, Tony Daher, Veena M Singh, Lyle J Arnold
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0223112

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