Resistance to HIV Integrase Inhibitors: About R263K and E157Q Mutations

The use of integrase inhibitors (INI) is increasing in antiretroviral therapies (ART) and INI are not all equal regarding genetic barrier to resistance. The aim of this manuscript was to review main in vivo and in vitro knowledge about two particular integrase resistance-associated mutations: R263K...

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Bibliographic Details
Main Authors: Charlotte Charpentier, Diane Descamps
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:Viruses
Subjects:
HIV
Online Access:http://www.mdpi.com/1999-4915/10/1/41