Differential Glial Activation in Early Epileptogenesis—Insights From Cell-Specific Analysis of DNA Methylation and Gene Expression in the Contralateral Hippocampus

Differential Glial Activation in Early Epileptogenesis—Insights From Cell-Specific Analysis of DNA Methylation and Gene Expression in the Contralateral Hippocampus

Background and Aims: Morphological changes in mesial temporal lobe epilepsy with hippocampal sclerosis (mTLE-HS) are well-characterized. Yet, it remains elusive whether these are a consequence of seizures or originate from a hitherto unknown underlying pathology. We recently published data on change...

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Bibliographic Details
Main Authors: Toni C. Berger, Magnus D. Vigeland, Hanne S. Hjorthaug, Cecilie G. Nome, Erik Taubøll, Kaja K. Selmer, Kjell Heuser
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Neurology
Subjects:
epilepsy
NeuN
TLE
glia
neuron
gene expression
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2020.573575/full

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