Raman spectroscopy as a quick tool to assess purity of extracellular vesicle preparations and predict their functionality

Raman spectroscopy as a quick tool to assess purity of extracellular vesicle preparations and predict their functionality

Extracellular vesicles (EVs) from a variety of stem cell sources are believed to harbour regenerative capacity, which may be exploited for therapeutic purposes. Because of EV interaction with other soluble secreted factors, EV activity may depend on the employed purification method, which limits cro...

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Bibliographic Details
Main Authors: Alice Gualerzi, Sander Alexander Antonius Kooijmans, Stefania Niada, Silvia Picciolini, Anna Teresa Brini, Giovanni Camussi, Marzia Bedoni
Format: Article
Language:English
Published: Taylor & Francis Group 2019-12-01
Series:Journal of Extracellular Vesicles
Subjects:
extracellular vesicles
stem cell
raman spectroscopy
size exclusion chromatography
ultracentrifugation
regenerative medicine
Online Access:http://dx.doi.org/10.1080/20013078.2019.1568780

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