Cardiac metabolic pathways affected in the mouse model of barth syndrome.

Cardiac metabolic pathways affected in the mouse model of barth syndrome.

Cardiolipin (CL) is a mitochondrial phospholipid essential for electron transport chain (ETC) integrity. CL-deficiency in humans is caused by mutations in the tafazzin (Taz) gene and results in a multisystem pediatric disorder, Barth syndrome (BTHS). It has been reported that tafazzin deficiency des...

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Bibliographic Details
Main Authors: Yan Huang, Corey Powers, Satish K Madala, Kenneth D Greis, Wendy D Haffey, Jeffrey A Towbin, Enkhsaikhan Purevjav, Sabzali Javadov, Arnold W Strauss, Zaza Khuchua
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4451073?pdf=render

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