Inhibition of leukemic cells by valproic acid, an HDAC inhibitor, in xenograft tumors

Inhibition of leukemic cells by valproic acid, an HDAC inhibitor, in xenograft tumors

Zhihua Zhang,1 Changlai Hao,1 Lihong Wang,1 Peng Liu,2 Lei Zhao,1 Cuimin Zhu,1 Xia Tian31Hematology Department, Affiliated Hospital of Chengde Medical College, Chengde, Hebei Province, 2Department of Medical Oncology, Shijiazhuang Municipal No 1 Hospital, Hebei Province, 3Department of Medical Oncol...

Full description

Bibliographic Details
Main Authors:	Zhang Z, Hao C, Wang L, Liu P, Zhao L, Zhu C, Tian X
Format:	Article
Language:	English
Published:	Dove Medical Press 2013-06-01
Series:	OncoTargets and Therapy
Online Access:	http://www.dovepress.com/inhibition-of-leukemic-cells-by-valproic-acid-an-hdac-inhibitor-in-xen-a13395

Similar Items

Mechanism of Growth Inhibition of Prostate Cancer Xenografts by Valproic Acid
by: Abhinav Sidana, et al.
Published: (2012-01-01)

HDAC inhibitor valproic acid increases CRABP2 expression and in combination with retinoic acid synergistically inhibits proliferation in glioblastoma cells
by: Yao, Lei
Published: (2016)

HDAC2 Inhibitor Valproic Acid Increases Radiation Sensitivity of Drug-Resistant Melanoma Cells
by: Bhuvanesh Sukhlal Kalal, et al.
Published: (2019-03-01)

Influence of the HDAC Inhibitor Valproic Acid on the Growth and Proliferation of Temsirolimus-Resistant Prostate Cancer Cells In Vitro
by: Jasmina Makarević, et al.
Published: (2019-04-01)

HDAC inhibitor valproic acid protects heart function through Foxm1 pathway after acute myocardial infarctionResearch in context
by: Shuo Tian, et al.
Published: (2019-01-01)

Valproic Acid as a Potential Inhibitor of Plasmodium falciparum Histone Deacetylase 1 (PfHDAC1): An in Silico Approach
by: Mohamed A. Abdallah Elbadawi, et al.
Published: (2015-02-01)

Rapid In Vivo Validation of HDAC Inhibitor-Based Treatments in Neuroblastoma Zebrafish Xenografts
by: Jagoda K Wrobel, et al.
Published: (2020-10-01)

In Vivo Screening Using Transgenic Zebrafish Embryos Reveals New Effects of HDAC Inhibitors Trichostatin A and Valproic Acid on Organogenesis.
by: Ling Li, et al.
Published: (2016-01-01)

Resistance after chronic application of the HDAC-inhibitor valproic acid is associated with elevated Akt activation in renal cell carcinoma in vivo.
by: Eva Juengel, et al.
Published: (2013-01-01)

Activity and mechanisms of action of novel organosulfur derivatives of the HDAC inhibitor Valproic Acid in human experimental models of non-small-cell lung cancer
by: Ulivi, Paola <1975>
Published: (2014)

Combination of erlotinib and a PARP inhibitor inhibits growth of A2780 tumor xenografts due to increased autophagy
by: Sui H, et al.
Published: (2015-06-01)

Cell type-specific anti-cancer properties of valproic acid: independent effects on HDAC activity and Erk1/2 phosphorylation
by: Bock Elisabeth, et al.
Published: (2010-07-01)

Exquisite Tumor Targeting by Salmonella A1-R in Combination with Caffeine and Valproic Acid Regresses an Adult Pleomorphic Rhabdomyosarcoma Patient-Derived Orthotopic Xenograft Mouse Model
by: Kentaro Igarashi, et al.
Published: (2020-02-01)

HDAC Inhibitors: Dissecting Mechanisms of Action to Counter Tumor Heterogeneity
by: Dimitris Karagiannis, et al.
Published: (2021-07-01)

Effects of the histone deacetylase inhibitor valproic acid on human pericytes in vitro.
by: Jakob Karén, et al.
Published: (2011-01-01)

Tumor Growth Mitigating Effects of Valproic Acid in Systemic Malignancies
by: Shailendra Kapoor
Published: (2015-01-01)

Valproic Acid and Thrombocytopenia
by: J Gordon Millichap
Published: (1996-08-01)

GCMS analysis of valproic acid metabolites and the effects of salicylate on valproic acid metabolism
by: Kassam, Jeanine Posset
Published: (2010)

Disruption of Planar Cell Polarity Pathway Attributable to Valproic Acid-Induced Congenital Heart Disease through Hdac3 Participation in Mice
by: Hong-Yu Duan, et al.
Published: (2018-01-01)

Oral administration of the pimelic diphenylamide HDAC inhibitor HDACi 4b is unsuitable for chronic inhibition of HDAC activity in the CNS in vivo.
by: Maria Beconi, et al.
Published: (2012-01-01)

Disease-stabilizing treatment based on all-trans retinoic acid and valproic acid in acute myeloid leukemia – identification of responders by gene expression profiling of pretreatment leukemic cells
by: Håkon Reikvam, et al.
Published: (2017-09-01)

Nanomaterials as potential transporters of HDAC inhibitors
by: Cristabelle De Souza, et al.
Published: (2020-06-01)

HDAC Inhibitors and RECK Modulate Endoplasmic Reticulum Stress in Tumor Cells
by: Yun Chen, et al.
Published: (2017-01-01)

Synergistic apoptosis induction in leukemic cells by the phosphatase inhibitor salubrinal and proteasome inhibitors.
by: Hannes C A Drexler
Published: (2009-01-01)

Involvement of HDAC1 and HDAC3 in the Pathology of Polyglutamine Disorders: Therapeutic Implications for Selective HDAC1/HDAC3 Inhibitors
by: Elizabeth A. Thomas
Published: (2014-05-01)

HDAC Inhibition with Valproate Improves Direct Cytotoxicity of Monocytes against Mesothelioma Tumor Cells
by: Duysinx, B., et al.
Published: (2022)

Valproic Acid and Carnitine Metabolism
by: J Gordon Millichap
Published: (1991-11-01)

Hepatic Fatalities and Valproic Acid
by: J Gordon Millichap
Published: (1996-04-01)

Choreiform Movements and Valproic Acid
by: J Gordon Millichap
Published: (1994-08-01)

Valproic Acid-induced Agranulocytosis
by: Hui-Chuan Hsu, et al.
Published: (2009-06-01)

Inhibition of leukemic apoptosis by antisense oligonucleotide.
Published: (1995)

Dihydrocoumarin, an HDAC Inhibitor, Increases DNA Damage Sensitivity by Inhibiting Rad52
by: Chin-Chuan Chen, et al.
Published: (2017-12-01)

The Lethality of [Pazopanib + HDAC Inhibitors] Is Enhanced by Neratinib
by: Laurence Booth, et al.
Published: (2019-07-01)

Valeric Acid Suppresses Liver Cancer Development by Acting as a Novel HDAC Inhibitor
by: Rui Han, et al.
Published: (2020-12-01)

HDAC3 Activity is Essential for Human Leukemic Cell Growth and the Expression of β-catenin, MYC, and WT1
by: Mandy Beyer, et al.
Published: (2019-09-01)

Valproic acid inhibits the release of soluble CD40L induced by non-nucleoside reverse transcriptase inhibitors in human immunodeficiency virus infected individuals.
by: Donna C Davidson, et al.
Published: (2013-01-01)

Valproic Acid Leads to an Increase in ROS Generation by Inhibiting the Deacetylation of Mitochondrial SOD
by: Lucas, Stephen Marc
Published: (2020)

Valproic acid attenuates traumatic spinal cord injury-induced inflammation via STAT1 and NF-κB pathway dependent of HDAC3
by: Shoubo Chen, et al.
Published: (2018-05-01)

Direct Conversion of Human Fibroblasts into Osteoblasts Triggered by Histone Deacetylase Inhibitor Valproic Acid
by: Hyeonjin Cha, et al.
Published: (2020-10-01)

In silico studies on modified hydroxamic acid and valporic acid as potential inhibitors for HDAC2
by: Naresh Kandakatla, et al.
Published: (2013-07-01)

Cannot write session to /tmp/vufind_sessions/sess_penkh8t5ktpab6bl29t0bc26lq