Mapping of positive selection sites in the HIV-1 genome in the context of RNA and protein structural constraints
<p>Abstract</p> <p>Background</p> <p>The HIV-1 genome is subject to pressures that target the virus resulting in escape and adaptation. On the other hand, there is a requirement for sequence conservation because of functional and structural constraints. Mapping the site...
Main Authors: | Snoeck Joke, Fellay Jacques, Bartha István, Douek Daniel C, Telenti Amalio |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-11-01
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Series: | Retrovirology |
Subjects: | |
Online Access: | http://www.retrovirology.com/content/8/1/87 |
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